Benefits seen for lowering systolic blood pressure, non-high-density lipoprotein cholesterol
By Lori Solomon HealthDay Reporter
MONDAY, March 11, 2024 (HealthDay News) — Nurse-led management can lower cardiovascular risk factors among individuals with HIV receiving antiretroviral therapy, according to a study published online March 5 in JAMA Network Open.
Christopher T. Longenecker, M.D., from University of Washington in Seattle, and colleagues assessed whether a multicomponent nurse-led strategy could improve systolic blood pressure (SBP) and non-high-density lipoprotein (HDL) cholesterol level in a diverse population of 297 people with HIV receiving antiretroviral therapy.
The researchers found that at 12 months, participants randomly assigned to the nurse intervention had a clinically significant 4.2-mm Hg lower SBP and 16.9-mg/dL lower non-HDL cholesterol level versus participants in the control arm. For women, there was a clinically meaningful but not statistically significant difference in SBP effect compared with men (four months: 11.8-mm Hg greater difference; eight months: 9.6 mm Hg; 12 months: 5.9 mm Hg).
“Findings of this trial suggest that nurse-led cardiovascular risk factor management in academic HIV clinics may lead to fewer cardiovascular events and should inform implementation of prevention programs for people with HIV,” the authors write. “Future research should explore the most effective components, dose, and mediators of these effects.”
Two authors disclosed ties to Gilead Sciences; one author disclosed ties to Theratechnologies.
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