Sedentary behavior is negatively associated with baseline and peak brachial artery diameters, superficial femoral artery diameters

TTVR plus optimal medical therapy yields greater improvement in disease-specific and general health status than OMT alone

Win ratio favoring valve replacement versus medical therapy alone was 2.02 at one year

Policies varied in the testing required, funding, processes after a positive screening result, and decision-making around concerning results

Orbital atherectomy does not yield greater minimal stent area or reduce rate of target vessel failure at one year

Light ex-smokers have significant reduction in CVD risk within 10 years of cessation, while risk disappears in >25 years for heavy ex-smokers

Early transcatheter aortic valve replacement bests clinical surveillance for reducing death, stroke, unplanned hospitalization

No impact seen on primary outcome among patients with asymptomatic severe aortic stenosis, myocardial fibrosis

Additional benefits include significant improvement in the physical and mental states of people with alcohol use disorder

Authors say these identified patients may benefit from more aggressive heart failure preventive strategies