Risk for all-cause death heightened with higher-volume drinking, particularly for women
By Lori Solomon HealthDay Reporter
FRIDAY, March 31, 2023 (HealthDay News) — Daily low or moderate alcohol intake is not significantly associated with all-cause mortality risk, but risk increased at higher consumption levels, particularly for women, according to a review published online March 31 in JAMA Network Open.
Jinhui Zhao, Ph.D., from University of Victoria in British Columbia, Canada, and colleagues conducted a systematic literature review to examine the association between alcohol use and all-cause mortality.
Based on 107 included cohort studies (4.8 million participants and 425,564 deaths available), the researchers found that when adjusting for potential confounding effects of sampling variation, former drinker bias, and other prespecified study-level quality criteria, there was no significant reduced risk for all-cause mortality among occasional (>0 to
“The importance of controlling for former drinker bias/misclassification is highlighted once more in our results which are consistent with prior studies showing that former drinkers have significantly elevated mortality risks compared with lifetime abstainers,” the authors write.
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