Incidence of all 10 prespecified CVDs decreased, but diagnoses of cardiac arrhythmias, valve disease, and thromboembolic diseases increased
Rare Predicted Loss-of-Function Variants, Polygenic Risk Score Linked to Risk of A-Fib
Odds ratio of 7.08 for atrial fibrillation for rare pLOF variants combined with high polygenic risk score
hs-cTnT Linked to MACE, Mortality in Rheumatoid Arthritis
Increased risk of MACE and all-cause mortality seen after adjustment for ASCVD risk, log hsCRP and for baseline ASCVD risk, DAS28-CRP