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But increase in cardiovascular disease mortality seen after more than 20 years of follow-up among older women

Agency’s action could widen access to the drug if more insurance companies decide to cover it

Risk for primary end-point event higher in patients in whom microplastics and nanoplastics were detected within the atheroma

Findings seen across cardiometabolic, common mental disorder, and mortality outcomes

Findings particularly strong for lower odds of severe coronary stenosis

Lower portal activity linked to older age, female sex and for Hispanic/Latinx, non-Hispanic Black, and other race patients

Yet prescription rates remain substantially lower than that seen for other guideline-recommended cardiometabolic therapies

Increase seen in physically and mentally unhealthy days during past month, years of life lost, age-adjusted all-cause mortality rate

Increased risk seen for atrial fibrillation, cerebrovascular disease, among others

Findings seen for body weight, body fat percentage, weight loss, and weight regain