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Highest prevalence seen for high blood pressure and not meeting aerobic physical activity guidelines, followed by obesity

Risk varies considerably across 26 examined cardiovascular conditions

15 percent relative reduction in the median Framingham CVD risk following eight weeks of time-restricted eating intervention

Elevated systolic BP and diabetes mellitus most important vascular risk factors for increased 10-year incident dementia risk at age 55

Greater glycemic variability is associated with increased risk for major adverse cardiovascular events

For adults aged 20 to 39 years, clinical criteria alone would yield 1.3 cases per 1,000 screened; adding genetic testing would increase the yield to 4.2 cases

Twenty-eight percent of trials used historical, external, or other control; nearly half used surrogate measure as a primary end point

At 24 and 48 months, greater BP control was seen in the lifestyle coaching group versus the usual care group

Findings seen for adults’ health and social functioning measured at ages 30 and 39 years

Some in-hospital therapies and prophylactic treatments may confer no benefit or are potentially harmful and should be reconsidered